Voltar
Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Time-course of health-related adaptations in response to combined training in hypertensive elderly: immune and autonomic modulation interactions

2018; UNIVERSIDADE EST.PAULISTA JÚLIO DE MESQUITA FILHO; Volume: 24; Issue: 4 Linguagem: Inglês

10.1590/s1980-6574201800040007

ISSN

1980-6574

Autores

Amanda Veiga Sardeli, Arthur Fernandes Gáspari, Wellington Martins dos Santos, Daisa Fabiele Godoi Moraes, Victor Bueno Gadelha, Lucas do Carmo Santos, Marina Lívia Venturini Ferreira, Simara Maria de J. Prudêncio, Ivan Luiz Padilha Bonfante, Bruno Rodrigues, Cláudia Regina Cavaglieri, Bo Fernhall, Mara Patrícia Traina Chacon‐Mikahil,

Tópico(s)

Stress Responses and Cortisol

Resumo

Aims: This article is a methodological description of a randomized clinical trial (ClinicalTrials.gov U1111-1181-4455) aiming to evaluate the time-course (monthly) and associations between blood pressure changes and other health-related adaptations in response to exercise training in hypertensive elderly. Methods: The patients will be randomized to a control or combined training group interventions (aerobic and resistance exercise), with monthly assessments in four months. Although, the changes in baseline blood pressure is the primary clinical outcome, the secondary outcomes include: body composition, cardiorespiratory fitness, muscle strength, arterial stiffness, baroreceptor sensitivity, cardiovascular autonomic modulation, inflammatory markers, oxidative stress, growth factors, tissue remodeling markers, metabolic profile, renal function, cognitive function and quality of life. Results: To support the understanding of the blood pressure changes in hypertensive elderly, a time-course of exercise-induced adaptations including cardiovascular and immunological adaptations are fundamental for research in this field. Conclusion: To investigate the time-course of combined training-induced adaptations including all the diverse aspects of health in hypertensive elderly a well-controlled protocol design is necessary, mainly to clarify the relationship between cardiovascular and immunological exercise-induced adaptations.

Referência(s)