Carta Acesso aberto Produção Nacional Revisado por pares

Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?

2018; Elsevier BV; Volume: 85; Issue: 7 Linguagem: Inglês

10.1016/j.biopsych.2018.10.003

ISSN

1873-2402

Autores

Theo G.M. van Erp, Esther Walton, Derrek P. Hibar, Lianne Schmaal, Wenhao Jiang, David C. Glahn, Godfrey D. Pearlson, Nailin Yao, Masaki Fukunaga, Ryota Hashimoto, Naohiro Okada, Hidenaga Yamamori, Vincent P. Clark, Bryon A. Mueller, Sonja M. C. de Zwarte, Roel A. Ophoff, Neeltje E.M. van Haren, Ole A. Andreassen, Tiril P. Gurholt, Oliver Gruber, Bernd Kraemer, Anja Richter, Vince D. Calhoun, Benedicto Crespo‐Facorro, Roberto Roiz‐Santiáñez, Diana Tordesillas‐Gutiérrez, Carmel M. Loughland, Stanley V. Catts, Janice M. Fullerton, Melissa J. Green, Frans Henskens, Assen Jablensky, Bryan Mowry, Christos Pantelis, Yann Quidé, Ulrich Schall, Rodney J. Scott, Murray J. Cairns, Marc L. Seal, Paul A. Tooney, Paul E. Rasser, Gavin Cooper, Cynthia Shannon Weickert, Thomas W. Weickert, Elliot Hong, Peter Kochunov, Raquel E. Gur, Ruben C. Gur, Judith M. Ford, Fabìo Macciardi, Daniel H. Mathalon, Steven G. Potkin, Adrian Preda, Fengmei Fan, Stefan Ehrlich, Margaret King, Lieuwe de Haan, Dick J. Veltman, Francesca Assogna, Nerisa Banaj, Pietro De Rossi, Mariangela Iorio, Fabrizio Piras, Gianfranco Spalletta, Edith Pomarol‐Clotet, Sinéad Kelly, Simone Ciufolini, Joaquim Raduà, Robin M. Murray, Tiago Reis Marques, Andrew Simmons, Stefan Borgwardt, Fabienne Schönborn‐Harrisberger, Anita Riecher‐Rössler, Renata Smieskova, Kathryn Alpert, Alessandro Bertolino, Aurora Bonvino, Annabella Di Giorgio, Emma Neilson, Andrew R. Mayer, Je‐Yeon Yun, Dara M. Cannon, Irina Lebedeva, Alexander S. Tomyshev, Tolibjohn Akhadov, В. Г. Каледа, Helena Fatouros‐Bergman, Lena Flyckt, Pedro G. P. Rosa, Maurício H. Serpa, Marcus V. Zanetti, Cyril Höschl, Antonín Škoch, Filip Španiel, David Tomeček, Andrew M. McIntosh, Heather C. Whalley, Christian Knöchel, Viola Oertel‐Knöchel, Fleur M. Howells, Dan J. Stein, Henk Temmingh, Anne Uhlmann, Carlos López‐Jaramillo, Danai Dima, Joshua I. Faskowitz, Boris A. Gutman, Neda Jahanshad, Paul M. Thompson, Jessica A. Turner, Lars Farde, Lena Flyckt, Helena Fatouros‐Bergman, Simon Červenka, Ingrid Agartz, Karin Collste, Pauliina Victorsson, Göran Engberg, Sophie Erhardt, Lilly Schwieler, Anna Malmqvist, Mikael Hedberg, Funda Orhan, Fredrik Piehl, Ingrid Agartz,

Tópico(s)

Advanced MRI Techniques and Applications

Resumo

In their letter to the editor, Vita and De Peri ( 1 Vita A. De Peri L. New meta- and mega-analyses of magnetic resonance imaging findings in schizophrenia: Do they really increase our knowledge about the nature of the disease process?. Biol Psychiatry. 2019; 85: e33 Abstract Full Text Full Text PDF Scopus (2) Google Scholar ) question whether new meta- and mega-analyses of magnetic resonance imaging (MRI) findings in schizophrenia increase our knowledge about the nature of the disease process. In general, meta- and mega-analyses provide objective methods to critically summarize a body of evidence regarding a particular question. As there had been no coordinated meta-analysis of cortical thickness and surface area abnormalities in schizophrenia, it is our view that this new, collaboratively conducted meta-analysis ( 2 van Erp T.G.M. Walton E. Hibar D.P. Schmaal L. Jiang W. Glahn D.C. et al. Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the Enhancing Neuro Imaging Genetics through Meta Analysis (ENIGMA) consortium. Biol Psychiatry. 2018; 84: 644-654 Abstract Full Text Full Text PDF PubMed Scopus (368) Google Scholar ) contributes to our knowledge on this question and offers information on the cross-site consistency of observed disease effects. Regional effects on cortical thickness and surface area can be difficult to summarize based on the traditional, literature-based, meta-analysis method, given the heterogeneity of analysis methods used in individual studies. New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?Biological PsychiatryVol. 85Issue 7PreviewWe read with interest the meta-analysis on cortical brain abnormalities in schizophrenia completed by the ENIGMA Schizophrenia Working Group (1). Full-Text PDF

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