Produção Nacional
Revisado por pares
Antioxidant activity of α and β -amyrin isolated from Myrcianthes pungens leaves
2018; Taylor & Francis; Volume: 34; Issue: 12 Linguagem: Inglês
10.1080/14786419.2018.1525715
ISSN1478-6427
AutoresBruna Karen Cardoso, Hérika Line Marko de Oliveira, Ulisses Z. Melo, Carla Maria Mariano Fernandez, Caio Franco de Araújo Almeida Campo, José Eduardo Gonçalves, Antônio Laverde, Mariza Barion Romagnolo, Giani Andréa Linde, Zilda Cristiani Gazim,
Tópico(s)Biological Activity of Diterpenoids and Biflavonoids
ResumoBrazil has a great variety of native plants which could be explored and among them guabiju (Myrcianthes pungens) stands out. Thus, this study consisted of isolating pentacyclic triterpenes, α and β-amyrin from guajibu leaves, and determine the antioxidant activity.The leaves were dried, pulverized and submitted to a dynamic maceration process with ethanol 96° GL, concentrated to obtain crude leaf extract (CLE). CLE was eluted with dichloromethane until total depletion, resulting in a dichloromethane fraction (FRDicl) which was concentrated and analyzed by GC/MS and NMR. The result of the chemical analysis revealed the presence of pentacyclic triterpenes of oleanane (β-amyrin), and ursane (α-amyrin) groups. The β-carotene bleaching method revealed a high antioxidant activity for the CLE as well as for FRDicl. The antioxidant protection equivalent to the trolox was of 137 and 129%, respectively at 500 µg/mL. The antioxidant potential of FRDicl can be explained by the presence of α and β-amyrins.
Referência(s)