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Apixaban to Prevent Venous Thromboembolism in Patients with Cancer

2018; Massachusetts Medical Society; Volume: 380; Issue: 8 Linguagem: Inglês

10.1056/nejmoa1814468

1533-4406

Marc Carrier, Karim Abou-Nassar, Ranjeeta Mallick, Vicky Tagalakis, Sudeep Shivakumar, Ariah Schattner, Philip Kuruvilla, Danny Hill, Silvana Spadafora, Katerine Marquis, Mateya Trinkaus, Anna Tomiak, Agnes Y.Y. Lee, Peter L. Gross, Grégoire Le Gal, Robert H. El-Maraghi, Glenwood D. Goss, Grégoire Le Gal, David Stewart, Timothy Ramsay, Marc Rodger, Debra Witham, Philip Wells,

Diagnosis and Treatment of Venous Diseases

Patients with active cancer have an increased risk of venous thromboembolism, which results in substantial morbidity, mortality, and health care expenditures. The Khorana score (range, 0 to 6, with higher scores indicating a higher risk of venous thromboembolism) has been validated to identify patients with cancer at elevated risk for this complication and may help select those who could benefit from thromboprophylaxis.