Artigo Acesso aberto Produção Nacional Revisado por pares

Design of inhibitors of thymidylate kinase from Variola virus as new selective drugs against smallpox: part II

2018; Taylor & Francis; Volume: 37; Issue: 17 Linguagem: Inglês

10.1080/07391102.2018.1554510

ISSN

1538-0254

Autores

Danielle Rodrigues Garcia, Felipe Rodrigues de Souza, Ana Paula de Campos Guimarães, Teodorico C. Ramalho, Alcino Palermo de Aguiar, Tanos C. C. França,

Tópico(s)

Bacillus and Francisella bacterial research

Resumo

Acknowledging the importance of studies toward the development of measures against terrorism and bioterrorism, this study aims to contribute to the design of new prototypes of potential drugs against smallpox. Based on a former study, nine synthetic feasible prototypes of selective inhibitors for thymidylate kinase from

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