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Trends in Serum Lipid Levels of a 10- and 13-Year-Old Population in Fukuroi City, Japan (2007–2017)

2018; Japan Epidemiological Association; Volume: 30; Issue: 1 Linguagem: Inglês

10.2188/jea.je20180164

1349-9092

Katsuyasu Kouda, Masayuki Iki, Yuki Fujita, Harunobu Nakamura, Kumiko Ohara, Takahiro Tachiki, Toshimasa Nishiyama,

Liver Disease Diagnosis and Treatment

Background: Current trends in serum lipid levels among children are likely to be important predictors of future cardiovascular disease prevalence.However, no studies have examined trends in low-density lipoprotein cholesterol (LDL-C) levels in Japanese children.Methods: We investigated trends in LDL-C levels from 2008 through 2017 and HDL-C levels from 2007 through 2017 in a population of 10-and 13-year-old children in Fukuroi City, Japan.We analyzed 17,838 children, accounting for 93.8% of all fifth and eighth graders in the entire city.Adverse lipid levels were defined as follows: 130 mg=dL or higher for LDL-C, and lower than 40 mg=dL for HDL-C.The Jonckheere-Terpstra and Cochran-Armitage tests were used to evaluate secular trends in mean serum lipid levels and prevalence of dyslipidemia, respectively.Results: There were no significant trends in BMI during the study period.In children aged 10 years, serum levels of LDL-C and HDL-C showed significant positive associations with calendar year during the study period for both sexes.A significant increase in HDL-C levels was observed in girls aged 13 years.On the other hand, no significant trends were observed in the prevalence of high LDL-C or low HDL-C regardless of sex or age, while the prevalence of high non-HDL-C showed a significant increase in boys.Conclusions: In the Fukuroi population, serum levels of LDL-C and HDL-C slightly increased in both boys and girls aged 10 years, and HDL-C levels slightly increased in girls aged 13 years, during the past decade.