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Early hospital readmission after kidney transplantation under a public health care system

2018; Wiley; Volume: 33; Issue: 3 Linguagem: Inglês

10.1111/ctr.13467

1399-0012

Melissa Gaspar, Marina Pontello Cristelli, Mayara Ivani de Paula, Laila Almeida Viana, Cláudia Rosso Felipe, Henrique Proença, Wilson Aguiar, Daniel Wagner de Castro Lima Santos, Hélio Tedesco‐Silva, José Osmar Medina Pestana,

Organ Transplantation Techniques and Outcomes

Abstract Early hospital readmission (EHR) is associated with increased mortality after kidney transplantation. This is influenced by population demographics and the comprehensiveness of the healthcare system. We investigated the incidence and risk factors associated with EHR and 1‐year patient and graft survivals. Methods We included all recipients of kidney transplant between 2011 and 2012. We excluded recipients younger than 18 years, retransplants and who died or lost the graft during the index hospital admission. Results Among 1175 recipients, the incidence of EHR was 26.6%. The main reasons for EHR were infection (67%), surgical complications (14%), and metabolic disturbances (11%). Independent risk factors associated with EHR were recipient age (OR = 1.95, 95% CI 1.46‐2.63, P < 0.001), CMV serology negative (OR = 2.2, 95% CI 1.31‐3.65, P = 0.003), use of rabbit anti‐thymocyte globulin (OR = 2.06, 95% CI 1.33‐3.13, P < 0.001), treatment for acute rejection during index hospitalization (OR = 1.68, 95% CI 1.15‐2.47, P = 0.008), and length of stay (OR = 1.72, 95% CI 1.18‐2.5, P = 0.005). Patient (88.8% vs 97.6%, P < 0.001) and death‐censored graft (97.4% vs 99.0%, P < 0.001) survivals were inferior comparing patients with and without EHR. Conclusion EHR was independently associated with mortality (OR 4.01, 95% CI 2.13‐7.54, P < 0.001), but its incidence and causes are directly related to the local characteristics of the population and healthcare system.