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BIBTEX RIS

Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant

2018; American Association for the Advancement of Science; Volume: 3; Issue: 30 Linguagem: Inglês

10.1126/sciimmunol.aau8714

ISSN

2470-9468

Autores

Stéphanie Boisson‐Dupuis, Noé Ramírez-Alejo, Zhi Li, Étienne Patin, Geetha Rao, Gaspard Kerner, Che Kang Lim, Dimitry N. Krementsov, Nicholas Hernandez, S. Cindy, Qian Zhang, Janet Markle, Rubén Martínez‐Barricarte, Kathryn Payne, Robert O. Fisch, Caroline Deswarte, Joshua Halpern, Matthieu Bouaziz, Jeanette Mulwa, Durga Sivanesan, Tomi Lazarov, Rodrigo Naves, Patricia García, Yuval Itan, Bertrand Boisson, Alix Checchi, Fabienne Jabot‐Hanin, Aurelié Cobat, Andrea Guennoun, Carolyn C. Jackson, Sevgi Pekcan, Zafer Çalışkaner, Jaime Inostroza, Beatriz Tavares Costa‐Carvalho, José Antônio Tavares de Albuquerque, Humberto Garcia‐Ortíz, Lorena Orozco, Tayfun Özçelık, A. Abid, Ismail Abderahmani Rhorfi, Hicham Souhi, Hicham Naji Amrani, Adil Zegmout, Frédéric Geissmann, Stephen W. Michnick, Ingrid Müller‐Fleckenstein, Bernhard Fleckenstein, Anne Puel, Michael J. Ciancanelli, Nico Marr, Hassan Abolhassani, María Elvira Balcells, Antônio Condino‐Neto, Alexis Strickler, Katia Abarca, Cory Teuscher, Hans D. Ochs, İsmail Reisli, Esra Hazar Sayar, Jamila El Baghdadi, Jacinta Bustamante, Lennart Hammarström, Stuart G. Tangye, Sandra Pellegrini, Lluís Quintana‐Murci, Laurent Abel, Jean‐Laurent Casanova,

Tópico(s)

Cytokine Signaling Pathways and Interactions

Resumo

Homozygosity for the P1104A missense variant of the TYK2 Janus kinase is common monogenic etiology of primary tuberculosis.

Referência(s)