Portal de Periódicos da CAPES

Artigo Produção Nacional Revisado por pares

BIBTEX RIS

PP.30.31

2015; Lippincott Williams & Wilkins; Volume: 33; Issue: Supplement 1 Linguagem: Inglês

10.1097/01.hjh.0000468655.22634.e9

1473-5598

Angela Cebolla Sousa, Rafaela Bernardes Rodrigues, Ana Carolina Arantes, Carolina Lôbo de Almeida Barros, T.C. Neiva, Brunella Mendonça Chinem, R. Miranda Rocha, Maicon Borges Euzébio, Weimar Kunz Sebba Barroso, Thiago Veiga Jardim, Ymara Cássia Luciana Araújo, Andréa Cristina de Sousa, Leandro Santos, H.G. Moreira, Karla Lorena Mendonça, Simone Dias Souza de Oliveira, Dalma Alves Pereira, P Jardim,

Healthcare Regulation

Objective: To evaluate dose-response relationship between salt intake and blood pressure. Design and method: Controlled trial with workers from university. The inclusion criteria: age between 20 and 60 years, both genders, main meal at home (at least fourfold a week). Individuals with blood pressure (BP) over 160/100 mmHg, diabetes and history of chronic renal disease or atherosclerosis were excluded. Trial was approved by Ethics Committee. Recruitment occurred at workplace using questionnaire and BP measurements. According to Brazilian Hypertension Guidelines participants were classified: normotensive (< 130/85 mmHg), high-normal BP (130–139/85–89 mmHg), hypertensive (> 140–159/90–99 mmHg) or controlled BP with less than two drugs. Participants were followed by 14 months, visits/ 4 weeks. They were instructed about reducing the intake of food with high levels of sodium, and received salt addition to the daily family consumption in quantities that were modified every 4 weeks (6 g, 5 g and 4 g). At each visit packages were returned for checking adhesion, as well as 24 h urinary sodium excretion were obtained. Results: Eighty patients were selected: 33 normotensive, 16 high-normal BP and 31 hypertensive. Salt intake and salt addition to the food were similar between groups. Average systolic (SBP) and diastolic BP (DBP) between the groups were different during all the visits (P < 0.05 - ANOVA), excepted among high-normal BP and hypertensive participants with similar SBP and DBP. SBP reduced 6mmHg (P < 0.05) in the high-normal BP group in the first 4 weeks, but this was not sustained at the end of the study. Mean urinary sodium excretion was 149.5 mEq/24 h (±65.6) at randomization and 155.9 mEq/24 h (±66.4) at the final visit for all groups. There was no correlation between urinary sodium excretion and BP between the groups. Average daily intake of salt addition was 3.3 g (±1.1) in the beginning and 1.8 (±0.5) in the final visit. There was no correlation between the different daily doses of provided salt and BP in any group (Pearson). Conclusions: Salt intake was higher than the recommended; the intervention only with the salt addition was not enough to reduce sodium intake. Intervention on sodium intake should include educational guidance.