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Reconstruction of the Genomes of Drug-Resistant Pathogens for Outbreak Investigation through Metagenomic Sequencing

2019; American Society for Microbiology; Volume: 4; Issue: 1 Linguagem: Inglês

10.1128/msphere.00529-18

2379-5042

Andre Mu, Jason C. Kwong, Nicole Isles, Anders Gonçalves da Silva, Mark B. Schultz, Susan A. Ballard, Courtney R. Lane, Glen P. Carter, Deborah A. Williamson, Torsten Seemann, Timothy P. Stinear, Benjamin P. Howden,

Antibiotic Resistance in Bacteria

The study results reported here perfectly demonstrate the power and promise of clinical metagenomics to recover genome sequences of important drug-resistant bacteria and to rapidly provide rich data that inform outbreak investigations and treatment decisions, independently of the need to culture the organisms.