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ICTV Virus Taxonomy Profile: Parvoviridae

2019; Microbiology Society; Volume: 100; Issue: 3 Linguagem: Inglês

10.1099/jgv.0.001212

1465-2099

Susan F. Cotmore, Mavis Agbandje‐McKenna, Marta Canuti, John A. Chiorini, Anna‐Maria Eis‐Hübinger, Joseph Hughes, Mario Mietzsch, Sejal Modha, Mylène Ogliastro, Judit J. Pénzes, David J. Pintel, Jianming Qiu, Maria Söderlund‐Venermo, Peter Tattersall, Peter Tijssen,

CRISPR and Genetic Engineering

Members of the family Parvoviridae are small, resilient, non-enveloped viruses with linear, single-stranded DNA genomes of 4-6 kb. Viruses in two subfamilies, the Parvovirinae and Densovirinae, are distinguished primarily by their respective ability to infect vertebrates (including humans) versus invertebrates. Being genetically limited, most parvoviruses require actively dividing host cells and are host and/or tissue specific. Some cause diseases, which range from subclinical to lethal. A few require co-infection with helper viruses from other families. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the Parvoviridae, which is available at www.ictv.global/report/parvoviridae.