Acylated flavonoid glycosides from Barringtonia racemosa
2019; Taylor & Francis; Volume: 34; Issue: 9 Linguagem: Inglês
10.1080/14786419.2018.1560290
ISSN1478-6427
AutoresQuach Thi Thanh Van, Le Thi Vien, Trần Thị Hồng Hạnh, Phan Thị Thanh Hương, Nguyen The Cuong, Nguyễn Phương Thảo, Nguyễn Huy Thuần, Nguyen Hai Dang, Nguyễn Văn Thành, Nguyễn Xuân Cường, Nguyễn Hoài Nam, Phan Văn Kiệm, Châu Văn Minh,
Tópico(s)Phytochemistry and Bioactive Compounds
ResumoUsing various chromatographic separations, three new acylated flavonoid glycosides, namely barringosides G-I (1-3), were isolated from the water-soluble extract of Barringtonia racemosa branches and leaves. The structure elucidation was performed by extensive analysis of the 1D and 2D NMR and HR-QTOF-MS data. Of the isolated compounds, barringoside I (3) showed moderate inhibitory effects on LPS-induced NO production in RAW264.7 cells with an IC50 of 52.48 ± 1.04 µM.
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