Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors
2019; American Association for the Advancement of Science; Volume: 5; Issue: 1 Linguagem: Inglês
10.1126/sciadv.aau3333
ISSN2375-2548
AutoresStephen S. Dominy, Casey Lynch, Florian Ermini, Małgorzata Benedyk, Agata Marczyk, Andrei W. Konradi, Mai Nguyen, Ursula Haditsch, Debasish Raha, Christina Griffin, Leslie J. Holsinger, Shirin Arastu‐Kapur, Samer E. Kaba, Alexander Lee, Mark I. Ryder, Barbara Potempa, Piotr Mydel, Annelie Hellvard, Karina Adamowicz, Hatice Hastürk, Glenn D. Walker, Eric C. Reynolds, Richard L. M. Faull, Maurice A. Curtis, Mike Dragunow, Jan Potempa,
Tópico(s)Oral and gingival health research
ResumoGingipains from Porphyromonas gingivalis drive Alzheimer’s pathology and can be blocked with small-molecule inhibitors.
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