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Human Immunodeficiency Virus (HIV) 2 Superinfection in a Patient Receiving Antiretroviral Therapy With Longstanding HIV-1 Viral Load Suppression

2019; Oxford University Press; Volume: 6; Issue: 4 Linguagem: Inglês

10.1093/ofid/ofz063

2328-8957

Filipa Ceia, André Silva‐Pinto, Ana Cláudia Carvalho, Carmela Piñeiro, Joaquim Soares, Rosário Serrão, António Sarmento,

HIV/AIDS Research and Interventions

Dual human immunodeficiency virus (HIV) 1 and HIV-2 superinfections are rare but challenging. A HIV-1-infected patient receiving effective antiretroviral therapy was investigated for a severe CD4+ cell count decline. HIV-2 superinfection was diagnosed and genotypic test revealed mutations conferring resistance to most drug class, limiting options for treatment.