Neurobiological relationships between astroglial Cx43 and stress-related responses
2019; Elsevier BV; Volume: 29; Linguagem: Inglês
10.1016/j.euroneuro.2018.11.736
ISSN1873-7862
AutoresBenjamin Portal, Stella Manta, Renaud Rovera, Nicola Di Lorenzo, Claire Rampon, Nicole Déglon, Nasser Haddjeri, Bruno P. Guiard,
Tópico(s)Neuroinflammation and Neurodegeneration Mechanisms
ResumoThe ammonium nickel phosphate (NH4NiPO4·H2O) nanorods were achieved via a facile hydrothermal method with urea acting as both NH4+ source and molecule template. The obtained samples were characterized by XRD, SEM, TEM, and XPS, which showed typically anisotropic growth of the crystals with rod-like structures. The diameter of the NH4NiPO4·H2O nanorods is less than 50 nm. The excellent glucose sensing performance was further obtained on the NH4NiPO4·H2O nanorods modified electrode, which have two corresponding linear regions of 5 μM–2100 μM and 2400 μM–5700 μM with the sensitivity of 459.4 μAmM−1 cm−2 and detection limit of 0.5 μM (S/N = 3) in the lower concentration range and the sensitivity of 250.2 μAmM−1 cm−2 and detection limit of 6 μM (S/N = 3) in the higher concentration range. Moreover, the as prepared sensor was also applied to analyze glucose concentration in serum samples, showing high possibility for real sample analysis. The highly nonenzymatic glucose sensing performance of NH4NiPO4·H2O nanorods may be due to its intrinsic layered crystal structure and rod-like morphology. The formation process of the NH4NiPO4·H2O nanorods and the corresponding glucose sensing mechanism were also discussed based on the analysis. These results could suggest that NH4NiPO4·H2O nanorods may be favorable electrochemical sensing materials for constructing non-enzymatic sensors.
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