Artigo Acesso aberto Produção Nacional Revisado por pares

Development of an Enzyme-Linked Immunosorbent Assay To Detect Antibodies Targeting Recombinant Envelope Protein 2 of Mayaro Virus

2019; American Society for Microbiology; Volume: 57; Issue: 5 Linguagem: Inglês

10.1128/jcm.01892-18

ISSN

1098-660X

Autores

Marcílio Jorge Fumagalli, William Marciel de Souza, Marília Farignoli Romeiro, Michell Charles de Souza Costa, Renata Dezengrini Slhessarenko, Luiz Tadeu Moraes Figueiredo,

Tópico(s)

Vector-Borne Animal Diseases

Resumo

Mayaro virus (MAYV) is a neglected arthropod-borne virus (arbovirus) antigenically clustered into the Semliki Forest complex group of Alphavirus genus ( Togaviridae family), maintained in an unclear zoonotic cycle involving mosquitoes from Haemagogus genus as the main vector. The genome is composed of a positive single-stranded RNA of 11.5 kb in length, which contains two genes that encode four nonstructural (nsP1 to nsP4) and five structural (C, E3, E2, 6K, and E1) proteins.

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