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Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”

2005; Wiley; Volume: 58; Issue: 6 Linguagem: Inglês

10.1002/ana.20703

1531-8249

Chris H. Polman, Stephen C. Reingold, Gilles Edan, Massimo Filippi, Hans‐Peter Hartung, Ludwig Kappos, Fred Lublin, Luanne M. Metz, Henry F. McFarland, Paul O’Connor, Magnhild Sandberg‐Wollheim, Alan J. Thompson, Brian G. Weinshenker, Jerry S. Wolinsky,

Rheumatoid Arthritis Research and Therapies

Abstract New diagnostic criteria for multiple sclerosis integrating magnetic resonance image assessment with clinical and other paraclinical methods were introduced in 2001. The “McDonald Criteria” have been extensively assessed and used since 2001. New evidence and consensus now strengthen the role of these criteria in the multiple sclerosis diagnostic workup to demonstrate dissemination of lesions in time, to clarify the use of spinal cord lesions, and to simplify diagnosis of primary progressive disease. The 2005 Revisions to the McDonald Diagnostic Criteria for MS should simplify and speed diagnosis, whereas maintaining adequate sensitivity and specificity. Ann Neurol 2005