Oxacillin-susceptible mecA-positive Staphylococcus aureus associated with processed food in Europe
2019; Elsevier BV; Volume: 82; Linguagem: Inglês
10.1016/j.fm.2019.01.021
ISSN1095-9998
AutoresNarciso M. Quijada, Marta Hernández, Elena-Alexandra Oniciuc, José María Eirós Bouza, Isabel Fernández-Natal, Martin Wagner, David Rodrı́guez-Lázaro,
Tópico(s)Bacterial Genetics and Biotechnology
ResumoWe report for the first time an oxacillin-susceptible mecA-positive Staphylococcus aureus (OS-MRSA) associated with a processed food product in Europe. One isolate (MRSA-ST5-type V SCCmec) was found in cheese among 600 food samples confiscated from air passengers from international flights in Vienna Airport (Austria). Type V SCCmec strains do not harbor functional mecI-mecR1 genes and in such strains mecA expression is regulated by the bla system (blaI-blaR1-blaZ). It has been recently reported that malfunctions in the bla system lead to the constitutive expression of mecA. The OS-MRSA reported in this study harbored the bla system on a plasmid and one deletion occurred in the blaR1 gene causing a frameshift variant that lead to an incomplete BlaR1 protein. This finding highlights the potential role of food as a neglected route of dissemination of emerging MRSA variants.
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