Carboxyl‐Terminal Region of Human and Bovine Erythrocyte Carbonic Anhydrases

1968; Wiley; Volume: 6; Issue: 2 Linguagem: Inglês

10.1111/j.1432-1033.1968.tb00436.x

ISSN

1432-1033

Autores

B. Andersson, P.O. Göthe, Torbjörn Nilsson, Per Olof Nyman, Lars Strid,

Tópico(s)

Cholinesterase and Neurodegenerative Diseases

Resumo

A methionine‐containing tryptic peptide from acetamidinated human carbonic anhydrase B has been isolated. This peptide has been shown to bridge a previously known carboxyl‐terminal fragment prepared by CNBr degradation with the rest of the enzyme molecule. Sequence studies on the methionine‐containing peptide have extended the previous knowledge of the carboxyl‐terminal sequence of the enzyme. Corresponding bridge peptides from human carbonic anhydrase C and acetamidinated bovine carbonic anhydrase B have also been isolated and their amino acid compositions have been determined.

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