Parkinson's Disease and Parkinsonism
2019; Elsevier BV; Volume: 132; Issue: 7 Linguagem: Inglês
10.1016/j.amjmed.2019.03.001
ISSN1555-7162
Autores Tópico(s)Genetic Neurodegenerative Diseases
ResumoParkinson's disease is a progressive neurodegenerative disease characterized by tremor and bradykinesia and is a common neurologic ailment. Male sex and advancing age are independent risk factors and, as the population ages, is taking an increasing toll on productivity and medical resources. There are a number of other extrapyramidal conditions that can make the diagnosis challenging. Unlike other neurodegenerative diseases, idiopathic Parkinson's disease has effective treatments that mitigate symptoms. Medications can improve day-to-day function and, in cases where medication does not give a sustained benefit or has significant side effects, treatments like deep brain stimulation result in improved quality of life.
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