Artigo Revisado por pares

HLA-A, -B, -C, -DRB1 and -DQB1 allele and haplotype frequencies of 1463 umbilical cord blood units typed in high resolution from Bogotá, Colombia

2019; Elsevier BV; Volume: 80; Issue: 7 Linguagem: Inglês

10.1016/j.humimm.2019.03.006

ISSN

1879-1166

Autores

Iván Aurelio Páez-Gutiérrez, David Guillermo Hernández, Diana Vanegas, Bernardo Camacho, Ana María Perdomo-Arciniegas,

Tópico(s)

Microbial infections and disease research

Resumo

Allele and haplotype frequencies were calculated from 1463 umbilical cord blood (UCB) units, from Bogotá (Colombia) donors, HLA-typed in high resolution. This is the first report using allele-level typed colombian samples of five HLA loci related to hematopoietic stem cell transplantation (HLA-A, -B, -C, -DRB1 and -DQB1). The most frequent haplotype found in our sample was A*24:02g ∼ B*35:43g ∼ C*01:02g ∼ DRB1*04:07g ∼ DQB1*03:02g (4.14%). Our data are available at the Allele Frequencies Net Database under the code AFND3604.

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