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BIBTEX RIS

Rheumatic heart disease in the modern era: recent developments and current challenges

2019; Brazilian Society of Tropical Medicine; Volume: 52; Linguagem: Inglês

10.1590/0037-8682-0041-2019

1678-9849

Matheus Tozatto Baptista Coelho Leal, Lívia Silva Araújo Passos, Felipe Vieira Guarçoni, JUAN PEDRO SARMENTO DE AGUIAR, Rafael Benjamim Rosa da Silva, Thiago Mendonça Nunes de Paula, Rafael Figueiredo Dos Santos, Maria Cecília Landim Nassif, Nayana F. A. Gomes, Timothy C. Tan, Maria Carmo Pereira Nunes,

Antimicrobial Resistance in Staphylococcus

Rheumatic heart disease (RHD) remains a major cause of preventable death and disability in children and young adults. Despite significant advances in medical technology and increased understanding of disease mechanisms, RHD continues to be a serious public health problem throughout the world, especially in low- and middle-income countries. Echocardiographic screening has played a key role in improving the accuracy of diagnosing RHD and has highlighted the disease burden. Most affected patients present with severe valve disease and limited access to life-saving cardiac surgery or percutaneous valve intervention, contributing to increased mortality and other complications. Although understanding of disease pathogenesis has advanced in recent years, key questions remain to be addressed. Preventing or providing early treatment for streptococcal infections is the most important step in reducing the burden of this disease.