Altered Protein Profiles in Platelets of Lupus Anticoagulant Positive Patients - New Players in LA-related Thrombosis?
2019; Thieme Medical Publishers (Germany); Linguagem: Inglês
10.1055/s-0039-1680153
ISSN2567-5761
AutoresLena Hell, Kristina Lurger, Lisa‐Marie Mauracher, Christina Maria Reumiller, Georg Schmidt, Silvia Koder, Alice Assinger, José Basílio, Johanna Gebhart, Cihan Ay, Ingrid Pabinger, Maria Zellner,
Tópico(s)Atherosclerosis and Cardiovascular Diseases
ResumoObjectives: Patients with lupus anticoagulants (LA) are at high risk to develop thromboembolism (TE). Previous studies have shown that platelets from LA positive patients show an increased activation status. The aim of this study was to gain deeper insights into the role of platelets in the antiphospholipid syndrome by investigating the platelet proteome of LA positive patients with TE (LA+TE+), LA positive patients without TE (LA+TE-) and of healthy controls.
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