Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018
2019; European Centre for Disease Prevention and Control; Volume: 24; Issue: 10 Linguagem: Inglês
10.2807/1560-7917.es.2019.24.10.1900147
ISSN1560-7917
AutoresDavid W. Eyre, Katy Town, Teresa Street, Leanne Barker, Nicholas D. Sanderson, Michelle Cole, Hamish Mohammed, Rachel Pitt, Maya Gobin, Charles Irish, Daniel Gardiner, James Sedgwick, Charles Beck, John Saunders, Deborah Turbitt, Clare Cook, Nick Phin, Bavithra Nathan, Paddy Horner, Helen Fifer,
Tópico(s)Syphilis Diagnosis and Treatment
ResumoWe describe detection in the United Kingdom (UK) of the drug-resistant Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate azithromycin resistance. Two female patients developed infection following contact with UK-resident men from the same sexual network linked to travel to Ibiza, Spain. One case failed treatment with ceftriaxone, and azithromycin and gentamicin, before successful treatment with ertapenem. Both isolates had indistinguishable whole-genome sequences. Urgent action is essential to contain this drug-resistant strain.
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