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The impact of attention deficit hyperactivity disorder in obsessive‐compulsive disorder subjects
2019; Wiley; Volume: 36; Issue: 6 Linguagem: Inglês
10.1002/da.22898
ISSN1520-6394
AutoresThiago Blanco‐Vieira, Matheus Felipe Aguiar Santos, Ygor Arzeno Ferrão, Albina Rodrigues Torres, Eurípedes C. Miguel, Michael H. Bloch, James F. Leckman, Maria Conceição do Rosário,
Tópico(s)Autism Spectrum Disorder Research
ResumoDepression and AnxietyVolume 36, Issue 6 p. 533-542 RESEARCH ARTICLE The impact of attention deficit hyperactivity disorder in obsessive-compulsive disorder subjects Thiago Blanco-Vieira, Thiago Blanco-Vieira orcid.org/0000-0003-3206-0932 Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, BrazilSearch for more papers by this authorMatheus Santos, Matheus Santos Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, BrazilSearch for more papers by this authorYgor A. Ferrão, Ygor A. Ferrão Department od Psychiatry, Porto Alegre Health Science Federal University, Porto Alegre, Brazil Brazilian OCD Research Consortium (CTOC), BrazilSearch for more papers by this authorAlbina R. Torres, Albina R. Torres Brazilian OCD Research Consortium (CTOC), Brazil Department of Psychiatry, Faculty of Medicine of Botucatu, State University of São Paulo, São Paulo, BrazilSearch for more papers by this authorEurípedes C. Miguel, Eurípedes C. Miguel Brazilian OCD Research Consortium (CTOC), Brazil Psychiatry Institute, Department of Psychiatry, School of Medicine, University of São Paulo, São Paulo, BrazilSearch for more papers by this authorMichael H. Bloch, Michael H. Bloch Child Study Center, Yale University, New Haven, ConnecticutSearch for more papers by this authorJames F. Leckman, James F. Leckman Child Study Center, Yale University, New Haven, ConnecticutSearch for more papers by this authorMaria C. do Rosario, Corresponding Author Maria C. do Rosario mariaceica.rosario@gmail.com Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil Brazilian OCD Research Consortium (CTOC), Brazil Child Study Center, Yale University, New Haven, Connecticut Correspondence Maria Conceição do Rosário, Department of Psychiatry Federal University of São Paulo (EPM/UNIFESP), R. Borges Lagoa, São Paulo 570 04038-031, Brazil. Email: mariaceica.rosario@gmail.comSearch for more papers by this author Thiago Blanco-Vieira, Thiago Blanco-Vieira orcid.org/0000-0003-3206-0932 Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, BrazilSearch for more papers by this authorMatheus Santos, Matheus Santos Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, BrazilSearch for more papers by this authorYgor A. Ferrão, Ygor A. Ferrão Department od Psychiatry, Porto Alegre Health Science Federal University, Porto Alegre, Brazil Brazilian OCD Research Consortium (CTOC), BrazilSearch for more papers by this authorAlbina R. Torres, Albina R. Torres Brazilian OCD Research Consortium (CTOC), Brazil Department of Psychiatry, Faculty of Medicine of Botucatu, State University of São Paulo, São Paulo, BrazilSearch for more papers by this authorEurípedes C. Miguel, Eurípedes C. Miguel Brazilian OCD Research Consortium (CTOC), Brazil Psychiatry Institute, Department of Psychiatry, School of Medicine, University of São Paulo, São Paulo, BrazilSearch for more papers by this authorMichael H. Bloch, Michael H. Bloch Child Study Center, Yale University, New Haven, ConnecticutSearch for more papers by this authorJames F. Leckman, James F. Leckman Child Study Center, Yale University, New Haven, ConnecticutSearch for more papers by this authorMaria C. do Rosario, Corresponding Author Maria C. do Rosario mariaceica.rosario@gmail.com Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil Brazilian OCD Research Consortium (CTOC), Brazil Child Study Center, Yale University, New Haven, Connecticut Correspondence Maria Conceição do Rosário, Department of Psychiatry Federal University of São Paulo (EPM/UNIFESP), R. Borges Lagoa, São Paulo 570 04038-031, Brazil. Email: mariaceica.rosario@gmail.comSearch for more papers by this author First published: 16 April 2019 https://doi.org/10.1002/da.22898Citations: 5Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract Background Recent findings suggest an association between attention deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD). Thus, we evaluated the clinical associated features of ADHD in a large sample of adult OCD patients. Methods A cross-sectional study including 955 adult patients with OCD from the Brazilian Research Consortium of Obsessive-Compulsive Spectrum Disorders (C-TOC). Clinical characteristics in adult OCD patients with and without comorbid ADHD were compared using Fisher's exact test, t-tests or Mann-Whitney tests. Bivariate analyses were followed by logistic regression analysis to identify clinical characteristics independently associated with ADHD comorbidity. Results The lifetime prevalence of ADHD in adult OCD patients was 13.7%. The current results indicate that OCD + ADHD patients were more severe, had an earlier onset of the obsessive-compulsive symptoms, a higher history of rheumatic fever, with higher frequencies of sensory phenomena and comorbidity with Tourette syndrome. They also had an increased risk for academic impairment and suicide attempts. Conclusion Adult OCD patients with ADHD present some specific clinical features and may represent a special subgroup of adult OCD. Future studies should focus on the development of interventions more tailored to the phenotype of this subgroup of patients. Citing Literature Volume36, Issue6FOCUS ON: COMORBIDITY WITHIN AND ACROSS MOOD AND ANXIETY DISORDERSJune 2019Pages 533-542 RelatedInformation
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