Portal de Periódicos da CAPES

Olfactory stimulus-induced temporal lobe seizures in limbic encephalitis

2019; Elsevier BV; Volume: 69; Linguagem: Inglês

10.1016/j.seizure.2019.05.005

1532-2688

Federica Avorio, Alessandra Morano, Martina Fanella, Jinane Fattouch, Mariarita Albini, Luca Manfredi Basili, Emanuele Cerulli Irelli, Giacomo Fisco, M. Manfredi, Anna Teresa Giallonardo, Carlo Di Bonaventura,

Peripheral Neuropathies and Disorders

Limbic encephalitis (LE) is a recently defined clinical entity, which might be associated with autoantibodies targeting either intracellular or neuronal surface antigens, with or without evidence of an underlying malignancy. Typical features of LE consist of subacute amnestic syndrome, psychiatric symptoms and focal seizures, which usually reflect the ictal involvement of the temporo-mesial structures and often represent the most striking manifestation at disease onset [1]. However, not only could the complex and elusive immune-mediated mechanisms underlying LE cause seizures during the acute phase, but also lead to the development of chronic epilepsy.