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Alterations in the gut microbiome and metabolism with coronary artery disease severity

2019; BioMed Central; Volume: 7; Issue: 1 Linguagem: Inglês

10.1186/s40168-019-0683-9

2049-2618

Honghong Liu, Xi Chen, Xiaomin Hu, Haitao Niu, Ran Tian, Hui Wang, Haiyu Pang, Lingjuan Jiang, Bintao Qiu, Xiuting Chen, Yang Zhang, Yiyangzi Ma, Si Tang, Hanyu Li, Siqin Feng, Shuyang Zhang, Chenhong Zhang,

Nutritional Studies and Diet

Coronary artery disease (CAD) is associated with gut microbiota alterations in different populations. Gut microbe-derived metabolites have been proposed as markers of major adverse cardiac events. However, the relationship between the gut microbiome and the different stages of CAD pathophysiology remains to be established by a systematic study.