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Effects of dietary reduced glutathione on the growth and antioxidant capacity of juvenile Atlantic salmon ( Salmo salar )

2019; Wiley; Volume: 25; Issue: 5 Linguagem: Inglês

10.1111/anu.12920

1365-2095

Jun Ma, Jing Zhang, Guoxiang Sun, Yanan Lou, Yong Li,

Animal Nutrition and Physiology

Aquaculture NutritionVolume 25, Issue 5 p. 1028-1035 ORIGINAL ARTICLE Effects of dietary reduced glutathione on the growth and antioxidant capacity of juvenile Atlantic salmon (Salmo salar) Jun Ma, Jun Ma Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China University of Chinese Academy of Sciences, Beijing, China Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, ChinaSearch for more papers by this authorJing Zhang, Jing Zhang Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China University of Chinese Academy of Sciences, Beijing, China Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, ChinaSearch for more papers by this authorGuoxiang Sun, Guoxiang Sun Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China Shandong Jincheng Biological Pharmaceutical Co., Ltd, Zibo, ChinaSearch for more papers by this authorYanan Lou, Yanan Lou Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China University of Chinese Academy of Sciences, Beijing, China Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, ChinaSearch for more papers by this authorYong Li, Corresponding Author Yong Li liyong@qdio.ac.cn orcid.org/0000-0003-3119-9860 Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China University of Chinese Academy of Sciences, Beijing, China Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China Correspondence Yong Li, Institute of Oceanology, Chinese Academy of Sciences, No. 7 Nanhai Road, Qingdao 266071, China. Email: liyong@qdio.ac.cnSearch for more papers by this author Jun Ma, Jun Ma Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China University of Chinese Academy of Sciences, Beijing, China Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, ChinaSearch for more papers by this authorJing Zhang, Jing Zhang Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China University of Chinese Academy of Sciences, Beijing, China Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, ChinaSearch for more papers by this authorGuoxiang Sun, Guoxiang Sun Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China Shandong Jincheng Biological Pharmaceutical Co., Ltd, Zibo, ChinaSearch for more papers by this authorYanan Lou, Yanan Lou Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China University of Chinese Academy of Sciences, Beijing, China Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, ChinaSearch for more papers by this authorYong Li, Corresponding Author Yong Li liyong@qdio.ac.cn orcid.org/0000-0003-3119-9860 Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China University of Chinese Academy of Sciences, Beijing, China Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China Correspondence Yong Li, Institute of Oceanology, Chinese Academy of Sciences, No. 7 Nanhai Road, Qingdao 266071, China. Email: liyong@qdio.ac.cnSearch for more papers by this author First published: 13 May 2019 https://doi.org/10.1111/anu.12920Citations: 6Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract To investigate the effects of dietary reduced glutathione (GSH) on the growth performance and antioxidant capacity of juvenile Atlantic salmon (Salmo salar), 396 juvenile fish with initial body weight of 143.07 ± 6.56 g were randomly distributed into four groups fed four diets with graded supplementation levels of GSH (0, 100, 200 and 400 mg/kg diet) for 83 days. The results showed that the appropriate GSH supplementation (100 and 200 mg/kg diet) significantly increased the growth performance, activities and gene mRNA expression levels of glutathione peroxidase (GPx) and glutathione transferase (GST), and the content of GSH and total antioxidant capacity (TAOC), whereas it significantly decreased activities and gene mRNA expression levels of superoxide dismutase (SOD) and catalase (CAT), and the content of malondialdehyde (MDA; p < 0.05). However, the excess dietary GSH (400 mg/kg diet) had an adverse effect on the all above indexes. Interestingly, the dietary GSH had the opposite effect on GSH-related antioxidant enzymes (GPx and GST) and other antioxidant enzymes (SOD and CAT). The results showed that the diet with 200 mg/kg GSH supplementation was optimal for the juvenile Atlantic salmon, which had a measured GSH content of 209.54 mg/kg. Citing Literature Volume25, Issue5October 2019Pages 1028-1035 RelatedInformation