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Human Leukocyte Antigen (HLA) class I and II datasets for sudanese

2019; Elsevier BV; Volume: 24; Linguagem: Inglês

10.1016/j.dib.2019.104027

2352-3409

Ameer Mohamed Dafalla, Hisham Atan Edinur, Mohammed Abdelwahed, Almutaz Abbas Elemam, Amel Abdeen Ibrahim, Ahmed A. Mohamadani, Mubarak Magzoub, Gehad ElGhazali,

Immunotherapy and Immune Responses

Sudan is located in the heart of Africa and surrounded by eight countries with people of different ethnic origins. Historical records show that the population of the Sudan is a mixture of Arabic, West Asian Arabic and sub-Saharan African elements. The present survey provides data on allele lineages, and haplotype frequencies of Human Leukocyte Antigen (HLA) class I (HLA-A and HLA-B) and class II (HLA-DR and -HLA-DQ) loci in 11 Sudanese populations. The sampled individuals are all local transplant donors who provided informed consent for HLA analyses on their blood samples and were registered at National Cancer Institute, University of Gezira, Wad Medani. The HLA class I and II data reported here can be subjected for future analyses of genetic structure and health in Sudan. These include as reference datasets for identifying the association between HLA and diseases and for designing donor recruitment strategies.