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Upregulation of Aldo-Keto-Reductase 1C1 and 1C3 is associated with poor prognosis in OPSCC independent of HPV status

2019; Thieme Medical Publishers (Germany); Linguagem: Inglês

10.1055/s-0039-1686048

1438-8685

Leonard Poluschkin, Ejm Speel, JP Klußmann, CU Hübbers,

Aldose Reductase and Taurine

Studies have shown that HPV16-positive OPSCC can be subdivided based on integration status (integrated, episomal and mixed forms). We showed integration did neither affect the levels of viral genes, nor those of virally disrupted human genes.