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Treatment patterns and costs among biologic-naive patients initiating apremilast or biologics for psoriatic arthritis

2019; Future Medicine; Volume: 8; Issue: 9 Linguagem: Inglês

10.2217/cer-2019-0034

2042-6313

Steven R. Feldman, Corey Pelletier, Kathleen Wilson, Rina Mehta, Matthew Brouillette, David M. Smith, Machaon Bonafede,

Rheumatoid Arthritis Research and Therapies

Aim: We evaluated treatment patterns and healthcare costs of initiating psoriatic arthritis (PsA) treatment with oral apremilast versus biologics. Methods: Claims data identified biologic-naive adults with PsA who initiated either apremilast or a biologic from 2013 to 2016. Results: Medication adherence was similar at 12 months (76.9 vs 73.4%; p = 0.175) between apremilast (n = 381) and matched biologic (n = 761) patients. Apremilast users had $12,715 lower total costs per-patient-per-month (p < 0.001), largely due to outpatient pharmacy and medical costs. Conclusion: Commercially insured patients with PsA initiating apremilast had adherence similar to those initiating biologics but lower total healthcare costs.