Artigo Acesso aberto Revisado por pares

Hepatitis B Virus Prevalence and Vaccination in Men Who Have Sex With Men in West Africa (CohMSM ANRS 12324—Expertise France)

2019; Oxford University Press; Volume: 6; Issue: 7 Linguagem: Inglês

10.1093/ofid/ofz249

ISSN

2328-8957

Autores

Ter Tiero Elias Dah, Clotilde Couderc, Alou Coulibaly, Malan Jean-Baptiste Kouamé, Mawuényégan Kouamivi Agboyibor, Issa Traoré, Gwenaëlle Maradan, Daniela Rojas Castro, Ephrem Mensah, Camille Anoma, Bintou Dembélé Keïta, Bruno Spire, Christian Laurent, Clotilde Couderc, Bruno Granouillac, Suzanne Izard, Christian Laurent, Laura March, Martine Peeters, Laetitia Serrano, Cyril Bérenger, Michel Bourrelly, Pierre-Julien Coulaud, Gwenaëlle Maradan, Marion Mora, Luis Sagaon‐Teyssier, Bruno Spire, Adeline Bernier, Paméla Palvadeau, Daniela Rojas Castro, Drissa Camara, Oumar Cissé, Alou Coulibaly, Bintou Dembélé Keïta, Fodié Diallo, Mahamadou Diarra, Abdoul Aziz Keita, Kader Maïga, Aly Ouologuem, Fodé Amara Traore, Niamkey Thomas Aka, Camille Anoma, Stéphane‐Alain Babo Yoro, Noufo Hamed Coulibaly, Rachelle Kotchi, Patrick Kouabenan, Malan Jean-Baptiste Kouamé, Kpassou Julien Lokrou, Frédéric Dibi N’guessan, Christian Coulibaly, Ter Tiero Elias Dah, Ousseni Ilboudo, Joseph Ouedraogo, Mamadou Ouedraogo, Elisabeth Thio, Juste Rodrigue Touré, Abdoulazziz Traoré, Issa Traoré, Fiffou Yougbare, Kouakou Kokouvi, Selom Agbomadji, Mawuényégan Kouamivi Agboyibor, Messan Attiogbe, Aléda Mawuli Badjassim, Agbégnigan Lorette Ekon, Anouwarsadat Kokouba, Ephrem Mensah, Diimiln Joseph Strauss Tablissi, Claver Anoumou Dagnra,

Tópico(s)

Liver Disease Diagnosis and Treatment

Resumo

Abstract Background Although men who have sex with men (MSM) are at high risk of hepatitis B virus (HBV) infection, they do not have access to vaccination in West Africa, which is a highly endemic region. We investigated HBV prevalence and associated factors, as well as acceptability and difficulties of vaccination in MSM enrolled in an operational research program in Burkina Faso, Côte d’Ivoire, Mali, and Togo. Methods We followed up 779 MSM in 2015–2018. Participants who were negative for both hepatitis B surface antigen (HBsAg) and antibodies (anti-HBs) at enrollment were offered HBV vaccination. Factors associated with HBV infection were identified using logistic regression models. Results Overall, HBV prevalence was 11.2% (95% confidence interval [CI], 9.0%–13.6%). It was lower in Togo than in Côte d’Ivoire (2.7% vs 17.3%; adjusted odds ratio [aOR], 0.12; 95% CI, 0.02–0.28) and higher in participants with 6+ recent male sexual partners (21.0% vs 9.3%; aOR, 1.48; 95% CI, 1.12–1.97). Of 528 participants eligible for vaccination, 484 (91.7%) were willing to be vaccinated and received at least 1 dose (ranging from 68.2% in Abidjan to 96.4% in Bamako; P < .001). Of the latter, 390 (80.6%) received 3 or 4 doses. The proportion of participants for whom the minimum required time between each dose was respected ranged from 10.9% in Bamako to 88.6% in Lomé (P < .001). Conclusions MSM in West Africa should be targeted more for HBV screening and vaccination. Although vaccination is well accepted by MSM, greater training of health care workers and education of MSM are required.

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