Portal de Periódicos da CAPES

Transgenic Metarhizium rapidly kills mosquitoes in a malaria-endemic region of Burkina Faso

2019; American Association for the Advancement of Science; Volume: 364; Issue: 6443 Linguagem: Inglês

10.1126/science.aaw8737

1095-9203

Brian Lovett, Etienne Bilgo, Souro Abel Millogo, Abel Kader Ouattarra, Issiaka Saré, Edounou Jacques Gnambani, Roch K. Dabiré, Abdoulaye Diabaté, Raymond J. St. Leger,

Insect and Arachnid Ecology and Behavior

Targeting mosquitoes to target malaria Anopheline mosquitoes transmit the malaria parasite, but the insects themselves are prone to their own infections. Lovett et al. engineered a specific fungal pathogen of anophelines to carry insect-selective toxins. The effectiveness of this fungus for controlling mosquitoes was trialed in near-field conditions in Burkina Faso in a setup called MosquitoSphere. Approximately 75% of wild insecticide-resistant mosquitoes released into the environment became infected with the transgenic fungus, causing population collapse within 45 days. Science , this issue p. 894