MAGE cancer-testis antigens protect the mammalian germline under environmental stress
2019; American Association for the Advancement of Science; Volume: 5; Issue: 5 Linguagem: Inglês
10.1126/sciadv.aav4832
ISSN2375-2548
AutoresKlementina Fon Tacer, Marhiah C. Montoya, Melissa J. Oatley, Tessa Lord, Jon M. Oatley, Jonathon Klein, Ramya Ravichandran, Heather Tillman, Minsoo Kim, Jon P. Connelly, Shondra M. Pruett‐Miller, Angie L. Bookout, Emily Binshtock, Marcin M. Kamiński, Patrick Ryan Potts,
Tópico(s)RNA Interference and Gene Delivery
ResumoMammals evolved testis-specific Mage-a genes to protect the male germline under starvation stress and are co-opted in cancer.
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