Artigo Acesso aberto Revisado por pares

MAGE cancer-testis antigens protect the mammalian germline under environmental stress

2019; American Association for the Advancement of Science; Volume: 5; Issue: 5 Linguagem: Inglês

10.1126/sciadv.aav4832

ISSN

2375-2548

Autores

Klementina Fon Tacer, Marhiah C. Montoya, Melissa J. Oatley, Tessa Lord, Jon M. Oatley, Jonathon Klein, Ramya Ravichandran, Heather Tillman, Minsoo Kim, Jon P. Connelly, Shondra M. Pruett‐Miller, Angie L. Bookout, Emily Binshtock, Marcin M. Kamiński, Patrick Ryan Potts,

Tópico(s)

RNA Interference and Gene Delivery

Resumo

Mammals evolved testis-specific Mage-a genes to protect the male germline under starvation stress and are co-opted in cancer.

Referência(s)