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BIBTEX RIS

Modulation of Serum Brain-Derived Neurotrophic Factor by a Single Dose of Ayahuasca: Observation From a Randomized Controlled Trial

2019; Frontiers Media; Volume: 10; Linguagem: Inglês

10.3389/fpsyg.2019.01234

ISSN

1664-1078

Autores

Raíssa Nóbrega de Almeida, Ana Cecília de Menezes Galvão, Flávia Santos da Silva, Erick Allan dos Santos Silva, Fernanda Palhano-Fontes, João Paulo Maia‐de‐Oliveira, Dráulio Barros de Araújo, Bruno Lobão‐Soares, Nicole Leite Galvão‐Coelho,

Tópico(s)

Tryptophan and brain disorders

Resumo

Serotonergic psychedelics are emerging as potential antidepressant therapeutic tools, as suggested in a recent randomized controlled trial with ayahuasca for treatment-resistant depression. Preclinical and clinical studies have suggested that serum brain-derived neurotrophic factor (BDNF) levels increase after treatment with serotoninergic antidepressants, but the exact role of BDNF as a biomarker for diagnostic and treatment of major depression is still poorly understood. Here we investigated serum BDNF levels in healthy controls (

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