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Amino acid-mediated Goldberg reactions between amides and aryl iodides

2004; Elsevier BV; Volume: 45; Issue: 11 Linguagem: Inglês

10.1016/j.tetlet.2004.01.119

1873-3581

Wei Deng, Yefeng Wang, Yan Zou, Lei Liu, Qing‐Xiang Guo,

Chemical Synthesis and Reactions

A highly general, experimentally simple, and inexpensive catalyst system was developed for the amidation of aryl iodides by using 5 mol % of CuI as catalyst, 20 mol % of an amino acid as ligand, and K3PO4 as base.