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VIRULIGN: fast codon-correct alignment and annotation of viral genomes

2018; Oxford University Press; Volume: 35; Issue: 10 Linguagem: Inglês

10.1093/bioinformatics/bty851

1367-4811

Pieter Libin, Koen Deforche, Ana Abecasis, Kristof Theys,

Plant Virus Research Studies

Abstract Summary Virus sequence data are an essential resource for reconstructing spatiotemporal dynamics of viral spread as well as to inform treatment and prevention strategies. However, the potential benefit of these applications critically depends on accurate and correctly annotated alignments of genetically heterogeneous data. VIRULIGN was built for fast codon-correct alignments of large datasets, with standardized and formalized genome annotation and various alignment export formats. Availability and implementation VIRULIGN is freely available at https://github.com/rega-cev/virulign as an open source software project. Supplementary information Supplementary data is available at Bioinformatics online.