Synthesis of New Ethyl 3-Amino-4-arylfuran-2-carboxylates
2002; Thieme Medical Publishers (Germany); Volume: 2002; Issue: 06 Linguagem: Inglês
10.1055/s-2002-25772
ISSN1437-210X
AutoresVincent Lisowski, Duc Nghia Vu, Feng Xiao, Sylvain Rault,
Tópico(s)Synthesis and Reactivity of Sulfur-Containing Compounds
ResumoAn efficient method for the preparation of new ethyl 3-amino-4-arylfuran-2-carboxylates is described. The synthesis proceeds via the corresponding hydroxyacrylonitrile sodium salt and an intermediate malonate vinyl ether. The last step of ring closure afforded the ethyl 3-amino-4-arylfuran-2-carboxylates in 15% to 40% yields.
Referência(s)