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Staminolactones A and B and Norstaminol A: Three Highly Oxygenated Staminane-Type Diterpenes from Orthosiphon stamineus

1999; American Chemical Society; Volume: 1; Issue: 9 Linguagem: Inglês

10.1021/ol990216+

1523-7060

Pavlos Stampoulis, Yasuhiro Tezuka, Arjun H. Banskota, Kim Qui Tran, Ikuo Saiki, Shigetoshi Kadota,

Phytochemicals and Antioxidant Activities

[formula: see text] Staminolactones A (1) and B (2) and norstaminol A (3), three highly oxygenated staminane-type diterpenes having mild cytotoxic activities against highly liver-metastatic colon 26-L5 carcinoma cells, were isolated from the aerial part of the Vietnamese medicinal plant Orthosiphon stamineus (Lamiaceae). Their structures were elucidated on the basis of the extensive spectral analyses.