Pd/C as a Highly Active Catalyst for Heck, Suzuki and Sonogashira Reactions
2002; Thieme Medical Publishers (Germany); Volume: 2002; Issue: 07 Linguagem: Inglês
10.1055/s-2002-32589
ISSN1437-2096
AutoresRoland G. Heidenreich, Klaus Köhler, Jürgen G.E. Krauter, Jörg Pietsch,
Tópico(s)Asymmetric Hydrogenation and Catalysis
ResumoA specially optimized air-stable Pd on activated carbon catalyst is demonstrated to be a highly active (TON up to 36,000), selective and convenient heterogeneous catalyst for CC couplings of aryl halides in Heck, Suzuki, and Sonogashira reactions. The Pd/C catalyst developed allows extremely low Pd concentrations (down to 0.0025 mol% for Heck coupling, 0.005 mol% for Suzuki coupling) and high conversions of aryl bromides within a few hours. Easy and complete Pd separation and recovery is possible.
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