From the "Ordeal Bean" (Physostigma venenosum) to the Ordeal of Alzheimer's Disease ----- Some of the Legacy of Percy Lavon Julian (1899 - 1975)
1998; Elsevier BV; Volume: 49; Issue: 1 Linguagem: Inglês
10.3987/1998-01-0009
ISSN1881-0942
Autores ResumoBJSE&I ---The Calabar bean, Physostigma venenosum, contains an alkaloid, physostigmine, which has therapeutic effects in glaucoma, pathological muscle fatigue and presenile dementia (Alzheimer's Disease), either as such or as suitable derivatives, all synthetically accessible by improvements of Percy Julian's first total synthesis in 1935.On Sunday, April 8, 1990, an Induction Ceremony took place at the National Inventors Hall of Fame in Akron, Ohio: among the ten inductees, such as Hermann Hollerith , inventor of the punched card system, or George Washington Carver , son of a slave and pioneer of agricultural research, was Percy Lavon Julian , grandson of a slave and pioneer in the chemistq of natural products of medicinal imporraucc.A? it says in its Charter: "The National Inventors Hall of Fame is dedicated to the individuals who conceived the great technological advances which this nation fosters through its patent system.The purpose of the Hall is to honor these inventors and bring public recognition to them and to their connibutions to the nation's welfare."The invention of the nominee must be covered by a particular patent, in Julian's case U.S.
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