Synthesis of 5H-Pyrazolo[4,3-c]quinolines
2004; Elsevier BV; Volume: 63; Issue: 8 Linguagem: Inglês
10.3987/com-04-10092
ISSN1881-0942
AutoresAlexandre V. Ivachtchenko, Olexiy V. Silin, Т. И. Савченко, Sergiy M. Kovalenko, Viktor M. Nikitchenko,
Tópico(s)Synthesis and Reactivity of Heterocycles
ResumoA convenient synthesis of 3-aryl-5H-pyrazolo[4,3-c]quinolines is described.The key reactions include alkylation of 3-aroyl-1H-quinolin-4-ones with alkyl halides in DMF in the presence of sodium hydride, followed by hydrazine-mediated cyclization of the alkylated products in acetic acid.
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