Synthesis of 1-indanones by intramolecular Friedel–Crafts reaction of 3-arylpropionic acids catalyzed by Tb(OTf)3
2004; Elsevier BV; Volume: 45; Issue: 8 Linguagem: Inglês
10.1016/j.tetlet.2003.12.085
ISSN1873-3581
AutoresDong‐Mei Cui, Chen Zhang, Masato Kawamura, Shigeru Shimada,
Tópico(s)Fluorine in Organic Chemistry
ResumoIntramolecular Friedel–Crafts acylation reaction of 3-arylpropionic acids was efficiently catalyzed by Tb(OTf)3 at 250 °C to give 1-indanones. Even deactivated 3-arylpropionic acids with halogen atoms on the aromatic ring can be cyclized in moderation to good yields.
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