N-Prop-2-ynylmaleimide. Application to Sequential One-pot Rh(I) Catalysed [2+2+2]-Alkyne Cyclotrimerisation–Imine Cycloaddition
2000; Elsevier BV; Volume: 56; Issue: 45 Linguagem: Inglês
10.1016/s0040-4020(00)00849-8
ISSN1464-5416
AutoresRonald Grigg, Visuvanathar Sridharan, Jun Wang, Juan Xu,
Tópico(s)Cyclopropane Reaction Mechanisms
ResumoRh(I) catalysed [2+2+2]-cyclotrimerisation of 1,6-diynes with monoynes in combination with stereospecific thermal or Ag(I) catalysed aldimine→(metallo) azomethine ylide→cycloaddition cascades affords rapid access to complex heterocyclic benzene derivatives in one-pot processes with the generation 5 new bonds, 4 stereocentres and 3 rings.
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