Direct, Metal-Free Synthesis of Benzyl Alcohols and Deuterated Benzyl Alcohols from p-Toluenesulfonylhydrazones Using Water as Solvent
2012; Thieme Medical Publishers (Germany); Volume: 44; Issue: 14 Linguagem: Inglês
10.1055/s-0031-1290372
ISSN1437-210X
AutoresErick Cuevas‐Yáñez, Ángel García-Muñoz, Aldo I. Ortega‐Arizmendi, Mario Alfredo García-Carrillo, E. Dı́az, Nelly González‐Rivas,
Tópico(s)Asymmetric Hydrogenation and Catalysis
ResumoA novel library of diverse alcohols was synthesized by metal-free couplings of diazoalkanes derived from p -toluenesulfonylhydrazones to water under reflux and microwave conditions, in high yields. In addition, this protocol was successfully applied in the synthesis of deuterium-labeled alcohols using deuterium oxide.
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