[Ru(DMSO)4]Cl2 catalyzes the α-alkylation of ketones by alcohols
2005; Elsevier BV; Volume: 46; Issue: 21 Linguagem: Inglês
10.1016/j.tetlet.2005.03.158
ISSN1873-3581
AutoresRicardo Martínez, Gabriel J. Brand, Diego J. Ramón, Miguel Yus,
Tópico(s)Catalytic Alkyne Reactions
ResumoThe electrophilic α-alkylation of ketones with alcohols was accomplished by a [Ru(DMSO)4]Cl2 catalyzed process, water being the only wasted material. The reaction can be successfully governed to produce either the expected ketones or their related alcohols only by changing the reaction conditions. When 2-aminobenzyl alcohol was used, a cyclization process took place to yield 2,3-disubstituted quinolines.
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