Nitrogen Heterocycles by Palladium-Catalyzed Cyclization of Amino-Tethered Vinyl Halides and Ketone Enolates
2003; American Chemical Society; Volume: 68; Issue: 14 Linguagem: Inglês
10.1021/jo034299q
ISSN1520-6904
AutoresDaniel Solé, Faı̈za Diaba, Josep Bonjoch,
Tópico(s)Cyclopropane Reaction Mechanisms
ResumoThe scope and limitations of Pd(0)-catalyzed intramolecular coupling of amino-tethered vinyl halides and ketone enolates as a methodology for the synthesis of nitrogen heterocycles have been studied. This reaction constitutes a synthetic procedure to obtain bridged, condensed, and monocyclic nitrogen-containing compounds.
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