Atom transfer addition and annulation reactions of propargyl iodomalononitrile
1992; Elsevier BV; Volume: 48; Issue: 11 Linguagem: Inglês
10.1016/s0040-4020(01)88881-5
ISSN1464-5416
AutoresDennis P. Curran, Churl Min Seong,
Tópico(s)Vanadium and Halogenation Chemistry
ResumoHeating of propargyl iodomalonitrile with mono-, di- or trisubstituted alkenes followed by reduction of the crude or isolated products with tributyltin hydride produces dicyano(methylene)cyclopentanes in good to excellent overall yield. This radical annulation is often highly regio and stereoselective. The mechanism is discussed.
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