An indium-promoted alternative to the Knoevenagel condensation of aldehydes with methyl acetoacetate
1999; Elsevier BV; Volume: 40; Issue: 22 Linguagem: Inglês
10.1016/s0040-4039(99)00724-8
ISSN1873-3581
AutoresLeo A. Paquette, Benjamen E. Kern, José Méndez-Andino,
Tópico(s)Oxidative Organic Chemistry Reactions
ResumoAddition of methyl (E)-4-bromo-3-methoxycrotonate to aldehydes in the presence of indium and water delivers β-hydroxy esters, acidic hydrolysis of which leads to Knoevenagel-like adducts.
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