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Szemfenéki angioid csíkok szisztémás betegségekben

2019; Akadémiai Kiadó; Volume: 160; Issue: 25 Linguagem: Inglês

10.1556/650.2019.31425

1788-6120

Dorottya Kriskó, Andrea Popper-Sachetti, Ágnes Sallai, Gábor László Sándor, Zoltán Zsolt Nagy, Zsuzsanna Szepessy,

Heterotopic Ossification and Related Conditions

Abstract: Angioid streaks are defined as the special morphological alteration of the fundus; the most common clinical manifestations are irregular, reddish brownish stripes around the optic nerve head or on the posterior pole. On the basis of histological examination, the cause of this phenomenon is the breaks and continuity deficiencies in the thin layer of Bruch membrane caused by the degeneration of elastic fibers. The aim of this study is to present the ocular complication of this rare entity through the description of three cases, and to draw attention to systemic diseases in the background. In our first and third cases, pseudoxanthoma elasticum (Grönblad–Strandberg syndrome) was in the background, while in our second case, hematological disease was confirmed. In our first and second cases, the ocular complication was the choroidal neovascularization, which we treated with intravitreal anti-VEGF injection. In our third case, the choroidal rupture was the ocular complication, caused by trauma. Angioid streaks on the fundus may be sub-phenomena of systemic diseases, the detection, differential diagnosis and treatment require interdisciplinary collaboration between associate physicians. Orv Hetil. 2019; 160(25): 994–1000.